Research articles
Management of patients with clinically suspected pyelonephritis in a resource poor setting
Authors:
M. Weerasekera ,
Faculty of Medical Sciences, University of Sri Jayewardenepura, LK
About M.
Department of Microbiology
N. Fernando,
Faculty of Medical Sciences, University of Sri Jayewardenepura, LK
About N.
Department of Microbiology
T. Welgamage,
Base Hospital, Tangalle, LK
K. Premarathna,
Base Hospital, Tangalle, LK
T.M. Wijesuriya,
Faculty of Medical Sciences, University of Sri Jayewardenepura, LK
About T.M.
Department of Microbiology
N. Ranasinghe
Base Hospital, Tangalle, LK
Abstract
Background: This study aimed to determine the aetiology, antimicrobial susceptibility pattern and the clinical response to antibiotics in pyelonephritis.
Methods: Bacterial culture and ABST, clinical response and onset of renal failure were analyzed in 240 clinically suspected pyelonephritis patients admitted to Medical Units at Base Hospital, Tangalle.
Results: Of the 240 patients 61% had culture positive UTI mainly due to E. Coli (94%). Pathogens were 100% sensitive to meropenem, imipenem and amikacin while it showed 96%, 93%, 85%, 81%, 60%, 36%, 13% sensitivity for nitrofurantoin netilmicin, gentamicin, co amoxiclav, ceftriaxone, ciprofloxacin and ampicillin. The average duration of fever in days after administration of IV antibiotic was: gentamicin 1.66, co amoxiclav 1.98, ceftriaxone 2.14, and ciprofloxacin 2.34.
Conclusion: Gentamicin was the most clinically effective antibiotic from the antibiotics used for the treatment of pyelonephritis in the selected patient population.
How to Cite:
Weerasekera, M., Fernando, N., Welgamage, T., Premarathna, K., Wijesuriya, T.M. and Ranasinghe, N., 2016. Management of patients with clinically suspected pyelonephritis in a resource poor setting. Journal of the Ceylon College of Physicians, 46(1-2), pp.16–18. DOI: http://doi.org/10.4038/jccp.v46i1-2.7739
Published on
12 May 2016.
Peer Reviewed
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