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Treatment time and outcome of thrombolytic therapy with streptokinase for acute ST Segment Elevation Myocardial Infarction (STEMI) in a District General Hospital of Sri Lanka: an audit

Authors:

W G Ranasinghe ,

District General Hospital, Kalutara, LK
About W G
Consultant Cardiologist
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P H R Kitsiri,

District General Hospital, Kalutara, LK
About P H R
Research Assistant, Colombo
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R Sutharson,

District General Hospital, Kalutara, LK
About R
Consultant Physician
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U Dissanayaka,

District General Hospital, Kalutara, LK
About U
Consultant Physician
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C Adikari,

District General Hospital, Kalutara, LK
About C
Consultant Physician
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W N Wijegunarathna,

District General Hospital, Kalutara, LK
About W N
Medical Officer
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J R Sendanayaka,

District General Hospital, Kalutara, LK
About J R
Medical Officer
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J N Jayamuni,

District General Hospital, Kalutara, LK
About J N
Medical Officer
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H Vithanage

District General Hospital, Kalutara, LK
About H
Medical officer
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Abstract

An audit was carried out to determine the treatment time and outcome of a convenient sample of acute uncomplicated STEMI patients who received thrombolysis with streptokinase between August 2013 and October 2014 at the District General Hospital, Kalutara (DGHK), with a view to optimizing STEMI care in the region.

Sixty-nine patients were analyzed for Ischemic Time, Door to Needle Time and in-hospital mortality, adverse cardiac events and complications following thrombolysis.

Median Ischemic and Door to Needle Times were 3 hours and 50 minutes respectively. The proportion of patients that achieved guideline recommended Door to Needle Time of 30 minutes and an optimal Ischaemic Time of 2 hours was low (30%). Although in-hospital mortality rate (3%) is low, 35% of patients had one or more complications following thrombolysis before discharge. Hypotension was the commonest complication (17%), while neither intracranial bleeding nor other adverse reactions to thrombolytic agent was reported.

The low proportion that received guideline recommended treatment times and the high proportion of in-hospital complications following thrombolysis indicate the need for optimizing STEMI care.

 

Journal of the Ceylon College of Physicians, 2014,45, 28-31

How to Cite: Ranasinghe, W.G. et al., (2015). Treatment time and outcome of thrombolytic therapy with streptokinase for acute ST Segment Elevation Myocardial Infarction (STEMI) in a District General Hospital of Sri Lanka: an audit. Journal of the Ceylon College of Physicians. 45(1-2), pp.28–31. DOI: http://doi.org/10.4038/jccp.v45i1-2.7724
Published on 27 Oct 2015.
Peer Reviewed

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